岡山大学大学院医歯薬学総合研究科呼吸器・乳腺内分泌外科(第2外科)は大正12年に開講し、現在同門会員723名を擁する大外科学教室です。とくに関連病院(各地の基幹病院)に関しては中四国随一の質および数を誇っています。砂田輝武、寺本滋前教授時代は心臓血管外科とともに呼吸器、消化器、内分泌、輸液と幅広い分野で学会をリードしてきた実績があります。平成2年4月に心臓血管外科が独立しましたが、消化器、呼吸器、内分泌、輸液の分野は呼吸器・乳腺内分泌外科に引き継がれており、心臓血管外科は現在も兄弟科としてお互いに協力しあって診療・研究を行っています。
詳しくはこちら
当科の歴史
1923年(大正12年)11月に西川義英教授が欧米留学より帰国し、第二外科学教室を創設してから実に80年以上の歴史を持つ「岡山大学大学院医歯薬学総合研究科呼吸器・乳腺内分泌外科」の歴代の教授と教室の沿革についてご紹介いたします。
詳しくはこちら
教職員紹介
自由と活気のある若さあふれる教室である「呼吸器・乳腺内分泌外科教室」の教職員を紹介いたします。「鬼手仏心」:外科医は残酷なほど大胆に手術するが、それは患者を治そうとするやさしい心によるものだ、ということを銘として切磋琢磨しながらも仕事を離れると大変和気あいあいとした雰囲気で教室員一同みんな仲がよいのが特徴です。
詳しくはこちら
最近の業績
2019
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Takeda T, Yamamoto H, Suzawa K, et al.
YES1 activation induces acquired resistance to neratinib in HER2-amplified breast and lung cancers.Cancer Sci. 2020 Mar;111(3):849-856. doi: 10.1111/cas.14289.
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Yoshioka T, Shien K, Takeda T, et al.
Acquired resistance mechanisms to afatinib in HER2-amplified gastric cancer cells.Cancer Sci. 2019 Aug;110(8):2549-2557. doi: 10.1111/cas.14089.
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Irie M, Otani S, Kurosaki T, et al.
Warm retrograde perfusion can remove more fat from lung grafts with fat embolism in a porcine model.
Gen Thorac Cardiovasc Surg. 2020 Apr;68(4):363-369. doi: 10.1007/s11748-019-01245-w.
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Nishiyama K, Taira N, Mizoo T, et al.
Influence of breast density on breast cancer risk: a case control study in Japanese women.
Breast Cancer. 2020 Mar;27(2):277-283. doi: 10.1007/s12282-019-01018-6.
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Sugimoto S, Kurosaki T, Otani S, et al.
Feasibility of lung transplantation from donors mechanically ventilated for prolonged periods
Surg Today. 2019 Mar;49(3):254-260. doi: 10.1007/s00595-018-1730-z.
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Tanaka S, Sugimoto S, Soh J, et al.
Long-term outcomes of pneumonectomy, back-table lung preservation, double-sleeve resection and reimplantation for advanced central lung cancer: the Oto procedure.
Eur J Cardiothorac Surg. 2019 Jul 1;56(1):213-214. doi: 10.1093/ejcts/ezy431.
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Tanaka S, Miyoshi K, Higo H, et al.
Lung transplant candidates with idiopathic pulmonary fibrosis and long-term pirfenidone therapy: Treatment feasibility influences waitlist survival.
Respir Investig. 2019 Mar;57(2):165-171. doi: 10.1016/j.resinv.2018.12.002.
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Mesaki K, Yamane M, Sugimoto S, et al.
SOCS3 overexpression in T cells ameliorates chronic airway obstruction in a murine heterotopic tracheal transplantation model
Surg Today. 2019 May;49(5):443-450. doi: 10.1007/s00595-018-1753-5.
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Taka H, Miyoshi K, Kurosaki T, et al.
Lung transplantation via cardiopulmonary bypass: excellent survival outcomes from extended criteria donors
Gen Thorac Cardiovasc Surg. 2019 Jul;67(7):624-632. doi: 10.1007/s11748-019-01067-w.
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Hirano Y, Sugimoto S, Yamamoto S, et al.
Prolonged warm ischemia exacerbated acute rejection after lung transplantation from donation after cardiac death in a mouse
Gen Thorac Cardiovasc Surg. 2020 Jan;68(1):57-62. doi: 10.1007/s11748-019-01181-9.
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Hashimoto K, Yamane M, Sugimoto S, et al.
Negative impact of recipient SPRED2 deficiency on transplanted lung in a mouse model
Transpl Immunol. 2019 Dec;57:101242. doi: 10.1016/j.trim.2019.101242.
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Suzawa K, Offin M, Lu D, et al.
Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer
Clin Cancer Res. 2019 Feb 15;25(4):1248-1260. doi: 10.1158/1078-0432.CCR-18-1640.
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Suzawa K, Soh J, Takahashi Y, et al.
Clinical outcome of patients with recurrent non-small cell lung cancer after trimodality therapy
Surg Today. 2019 Jul;49(7):601-609. doi: 10.1007/s00595-019-1774-8.
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Suzawa K, Offin M, Schoenfeld AJ, et al.
Acquired MET Exon 14 Alteration Drives Secondary Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in EGFR-Mutated Lung Cancer
JCO Precis Oncol. 2019;3:PO.19.00011. doi: 10.1200/PO.19.00011.
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Miyauchi S, Shien K, Tanaka M, et al.
Pulmonary resection in a prone position for lung cancer invading the spine
Gen Thorac Cardiovasc Surg. 2020 Mar;68(3):298-301. doi: 10.1007/s11748-019-01113-7.
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Sato H, Soh J, Aoe K, et al.
Droplet digital PCR as a novel system for the detection of microRNA‑34b/c methylation in circulating DNA in malignant pleural mesothelioma.
Int J Oncol. 2019 Jun;54(6):2139-2148. doi: 10.3892/ijo.2019.4768.
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Namba K, Shien K, Takahashi Y, et al.
Activation of AXL as a Preclinical Acquired Resistance Mechanism Against Osimertinib Treatment in EGFR-Mutant Non-Small Cell Lung Cancer Cells.
Mol Cancer Res. 2019 Feb;17(2):499-507. doi: 10.1158/1541-7786.MCR-18-0628.
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Namba K, Tomida S, Matsubara T, et al.
Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma.
BMC Cancer. 2019 Feb 26;19(1):175. doi: 10.1186/s12885-019-5374-1.
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Konishi Y, Miyoshi K, Kurosaki T, et al.
Airway bacteria of the recipient but not the donor are relevant to post-lung transplant pneumonia.
Gen Thorac Cardiovasc Surg. 2020 Aug;68(8):833-840. doi: 10.1007/s11748-019-01273-6.
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Kurosaki T, Otani S, Miyoshi K, et al.
Favorable survival even with high disease-specific complication rates in lymphangioleiomyomatosis after lung transplantation-long-term follow-up of a Japanese center.
Clin Respir J. 2020 Feb;14(2):116-123. doi: 10.1111/crj.13108. Epub 2019 Nov 28.
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Soh J, Toyooka S, Okumura N, et al.
Impact of pathological stage and histological subtype on clinical outcome of adjuvant chemotherapy of paclitaxel plus carboplatin versus oral uracil-tegafur for non-small cell lung cancer: subanalysis of SLCG0401 trial.
Int J Clin Oncol. 2019 Nov;24(11):1367-1376. doi: 10.1007/s10147-019-01508-9.
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Kurihara E, Shien K, Torigoe H, et al.
Ganetespib in Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor-resistant Non-small Cell Lung Cancer.
Anticancer Res. 2019 Apr;39(4):1767-1775. doi: 10.21873/anticanres.13283.
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Ogoshi Y, Shien K, Yoshioka T, et al.
Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations.
Oncol Lett. 2019 Mar;17(3):2729-2736. doi: 10.3892/ol.2019.9908.
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Sugimoto S, Yamamoto H, Kurosaki T, et al.
Impact of chronic lung allograft dysfunction, especially restrictive allograft syndrome, on the survival after living-donor lobar lung transplantation compared with cadaveric lung transplantation in adults: a single-center experience.
Surg Today. 2019 Aug;49(8):686-693. doi: 10.1007/s00595-019-01782-0.
2018
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Yamamoto H, Yatabe Y, Toyooka S, et al.
Inherited lung cancer syndromes targeting never smokers
Transl Lung Cancer Res. 2018 Aug;7(4):498-504. doi: 10.21037/tlcr.2018.06.01.
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Yamamoto H, Toyooka S, Ninomiya T, et al.
Therapeutic Potential of Afatinib for Cancers with ERBB2 (HER2) Transmembrane Domain Mutations G660D and V659E
Oncologist. 2018 Feb;23(2):150-154. doi: 10.1634/theoncologist.2017-0345.
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Yamamoto H, Sugimoto S, Tanaka S, et al.
A single-nucleotide polymorphism in a gene modulating glucocorticoid sensitivity is associated with the decline in total lung capacity after lung transplantation.
Surg Today. 2019 Mar;49(3):268-274. doi: 10.1007/s00595-018-1717-9.
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Toyooka S, Okumura N, Nakamura H, et al.
A Multicenter Randomized Controlled Study of Paclitaxel plus Carboplatin versus Oral Uracil-Tegafur as the Adjuvant Chemotherapy in Resected Non-Small Cell Lung Cancer.
J Thorac Oncol. 2018 May;13(5):699-706. doi: 10.1016/j.jtho.2018.02.015.
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Sugimoto S, Miyoshi K, Kurosaki T, et al.
Favorable survival in lung transplant recipients on preoperative low-dose, as compared to high-dose corticosteroids, after hematopoietic stem cell transplantation
Int J Hematol. 2018 Jun;107(6):696-702. doi: 10.1007/s12185-018-2417-3.
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Mesaki K, Sugimoto S, Otani S, et al.
Pneumatosis intestinalis after lung transplantation for pulmonary graft-versus-host disease
J Thorac Dis. 2018 Jan;10(1):E42-E45. doi: 10.21037/jtd.2017.11.121.
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Otani S, Kurosaki T, Sugimoto S, et al.
Unilateral lung transplantation using intact bilateral upper lobes
J Thorac Cardiovasc Surg. 2018 Jul;156(1):e35-e38. doi: 10.1016/j.jtcvs.2018.03.003.
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Sugimoto S, Yamane M, Otani S, et al.
Airway complications have a greater impact on the outcomes of living-donor lobar lung transplantation recipients than cadaveric lung transplantation recipients
Surg Today. 2018 Sep;48(9):848-855. doi: 10.1007/s00595-018-1663-6.
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Kurosaki T, Miyoshi K, Otani S, et al.
Low-risk donor lungs optimize the post-lung transplant outcome for high lung allocation score patients
Surg Today. 2018 Oct;48(10):928-935. doi: 10.1007/s00595-018-1670-7.
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Okada M, Yamane M, Yamamoto S, et al.
SPRED2 deficiency may lead to lung ischemia-reperfusion injury via ERK1/2 signaling pathway activation
Surg Today. 2018 Dec;48(12):1089-1095. doi: 10.1007/s00595-018-1696-x.
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Habu T, Soh J, Toji T, et al.
Myoepithelioma occurring in the posterior mediastinum harboring EWSR1 rearrangement: a case report
Jpn J Clin Oncol. 2018 Sep 1;48(9):851-854. doi: 10.1093/jjco/hyy100.
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Tanaka S, Sugimoto S, Kurosaki T, et al.
Donor-derived cell-free DNA is associated with acute rejection and decreased oxygenation in primary graft dysfunction after living donor-lobar lung transplantation
Sci Rep. 2018 Oct 18;8(1):15366. doi: 10.1038/s41598-018-33848-3.
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Sugimoto S, Kurosaki T, Otani S, et al.
Feasibility of lung transplantation from donors mechanically ventilated for prolonged periods
Surg Today. 2019 Mar;49(3):254-260. doi: 10.1007/s00595-018-1730-z.
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Sugimoto S
Can pretransplant computed-tomographic assessment predict outcomes after lung transplantation?
J Thorac Dis. 2018 Oct;10(10):5652-5654. doi: 10.21037/jtd.2018.09.51.
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Takahashi Y, Shien K, Tomida S, et al.
Comparative mutational evaluation of multiple lung cancers by multiplex oncogene mutation analysis.
Cancer Sci. 2018 Nov;109(11):3634-3642. doi: 10.1111/cas.13797.
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Sato H, Yamamoto H, Sakaguchi M, et al.
Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer.
Cancer Sci. 2018 Oct;109(10):3183-3196. doi: 10.1111/cas.13763.
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Sato H, Soh J, Hotta K, et al.
Is Surgery after Chemoradiotherapy Feasible in Lung Cancer Patients with Superior Vena Cava Invasion?
Ann Thorac Cardiovasc Surg. 2018 Jun 20;24(3):131-138. doi: 10.5761/atcs.oa.18-00027.
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Torigoe H, Yamamoto H, Sakaguchi M, et al.
Tumor-suppressive effect of LRIG1, a negative regulator of ErbB, in non-small cell lung cancer harboring mutant EGFR.
Carcinogenesis. 2018 May 3;39(5):719-727. doi: 10.1093/carcin/bgy044.
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Torigoe H, Shien K, Takeda T, et al.
Therapeutic strategies for afatinib-resistant lung cancer harboring HER2 alterations.
Cancer Sci. 2018 May;109(5):1493-1502. doi: 10.1111/cas.13571.
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Yoshioka T, Shien K, Namba K, et al.
Antitumor activity of pan-HER inhibitors in HER2-positive gastric cancer.
Cancer Sci. 2018 Apr;109(4):1166-1176. doi: 10.1111/cas.13546.
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Sato H, Sakaguchi M, Yamamoto H, et al.
Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma.
Oncogenesis. 2018 Jan 24;7(1):11. doi: 10.1038/s41389-017-0017-3.
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Miura A, Mori T, Yoshida A, et al.
Primary adenocarcinoma of the trachea revealing a mucinous bronchial gland cell origin.
Pathol Res Pract. 2018 May;214(5):796-799. doi: 10.1016/j.prp.2018.03.006.
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Tanaka S, Miyoshi K, Higo H, et al.
Lung transplant candidates with idiopathic pulmonary fibrosis and long-term pirfenidone therapy: Treatment feasibility influences waitlist survival.
Respir Investig. 2019 Mar;57(2):165-171. doi: 10.1016/j.resinv.2018.12.002.
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Shien T, Doihara H, Sato N, et al.
Serum lipid and bone metabolism effects of Toremifene vs. Letrozole as adjuvant therapy for postmenopausal early breast cancer patients: results of a multicenter open randomized study.
Cancer Chemother Pharmacol. 2018 Feb;81(2):269-275. doi: 10.1007/s00280-017-3491-6
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Sasada S, Shien T, Iwata H, et al.
Current status of postmastectomy radiation therapy in T1-2 breast cancer with limited positive lymph nodes in Japan: Japan Clinical Oncology Group Survey.
Breast Cancer. 2018 Sep;25(5):626-627. doi: 10.1007/s12282-018-0855-7.
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Takahashi Y, Shien T, Sakamoto A, et al.
Current Multidisciplinary Approach to Fertility Preservation for Breast Cancer Patients.
Acta Med Okayama. 2018 Apr;72(2):137-142. doi: 10.18926/AMO/55854.
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Oka K, Shien T, Otsuka F, et al.
Thyroid follicular carcinoma in a teenager: A case report.
J Gen Fam Med. 2018 Jun 21;19(5):170-172. doi: 10.1002/jgf2.185.
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Oka K, Yasuda M, Shien T, et al.
A marked goiter involved in Marine-Lenhart syndrome.
J Gen Fam Med. 2018 Nov 24;20(1):37-38. doi: 10.1002/jgf2.220.
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Shien T
The eligibility of primary tumor resection for de novo stage IV breast cancer patients
Transl Cancer Res 2018;7(Suppl 5):S604-S607. doi: 10.21037/tcr.2018.05.28
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Iwamoto T, Taira N, Fujisawa T, et al.
Hormonal Therapy Resistant Estrogen-receptor Positive Metastatic Breast Cancer Cohort (HORSE-BC) Study : Current Status of Treatment Selection in Japan
Acta Med Okayama. 2018 Aug;72(4):369-374. doi: 10.18926/AMO/56172.
2017
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Sugimoto S, Yamane M, Miyoshi K, et al.
Pulmonary artery patch for an inadequate donor atrial cuff in the absence of donor pericardium in lung transplantation
Surg Today. 2017 Mar;47(3):399-401. doi: 10.1007/s00595-016-1370-0.
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Maki Y, Toyooka S, Soh J, et al.
Early postoperative complications after middle lobe-preserving surgery for secondary lung cancer
Surg Today. 2017 May;47(5):601-605. doi: 10.1007/s00595-016-1413-6.
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Okada M, Sugimoto S, Yamane M, et al.
Immunoglobulin G4-related disease presenting as an intrapericardial tumor
Jpn J Clin Oncol. 2017 Jan;47(1):88-89. doi: 10.1093/jjco/hyw161
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Sugimoto S, Otani S, Ohki T, et al.
Lung retransplantation in an adult 13 years after single lobar transplant in childhood
Gen Thorac Cardiovasc Surg. 2017 Sep;65(9):539-541. doi: 10.1007/s11748-016-0732-2.
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Hashimoto K, Miyoshi K, Mizutani H, et al.
Successful Lung Transplantation for Pulmonary Disease Associated With Erdheim-Chester Disease
Ann Thorac Surg. 2017 Jul;104(1):e13-e15. doi: 10.1016/j.athoracsur.2017.02.020.
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Kawana S, Yamamoto H, Maki Y, et al.
Reconstruction of Anterior Chest Wall with Polypropylene Mesh: Two Primary Sternal Chondrosarcoma Cases
Acta Med Okayama. 2017 Jun;71(3):259-262. doi: 10.18926/AMO/55210.
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Tanaka S, Miyoshi K, Sugimoto S, et al.
Successful Lung Transplantation Using a Deceased Donor Mechanically Ventilated for Ten Months
Ann Thorac Surg. 2017 Aug;104(2):e177-e179. doi: 10.1016/j.athoracsur.2017.03.019.
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Hirano Y, Sugimoto S, Mano T, et al.
Prolonged Administration of Twice-Daily Bolus Intravenous Tacrolimus in the Early Phase After Lung Transplantation
Ann Transplant. 2017 Aug 11;22:484-492. doi: 10.12659/aot.904225.
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Yamamoto H, Sugimoto S, Otani S, et al.
Postoperative pyoderma gangrenosum exacerbated by granulocyte-colony stimulating factor after lung cancer surgery
Jpn J Clin Oncol. 2017 Oct 1;47(10):991-992. doi: 10.1093/jjco/hyx121.
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Shien K, Papadimitrakopoulou VA, Ruder D, et al.
JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non-Small Cell Lung Cancer
Mol Cancer Ther. 2017 Oct;16(10):2234-2245. doi: 10.1158/1535-7163.MCT-17-0148.
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Shien K, Toyooka S, Soh J, et al.
Is tumor location an independent prognostic factor in locally advanced non-small cell lung cancer treated with trimodality therapy?
J Thorac Dis. 2017 May;9(5):E489-E491. doi: 10.21037/jtd.2017.03.183.
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Chen H, Shien K, Suzawa K, et al.
Elacridar, a third-generation ABCB1 inhibitor, overcomes resistance to docetaxel in non-small cell lung cancer
Oncol Lett. 2017 Oct;14(4):4349-4354. doi: 10.3892/ol.2017.6678.
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Takeda T, Yamamoto H, Kanzaki H, et al.
Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer
PLoS One. 2017 Feb 3;12(2):e0171356. doi: 10.1371/journal.pone.0171356.
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Iwamoto T, Katagiri T, Niikura N, et al.
Immunohistochemical Ki67 after short-term hormone therapy identifies low-risk breast cancers as reliably as genomic markers
Oncotarget. 2017 Apr 18;8(16):26122-26128. doi: 10.18632/oncotarget.15385.
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Kochi M, Iwamoto T, Niikura N, et al.
Tumour-infiltrating lymphocytes (TILs)-related genomic signature predicts chemotherapy response in breast cancer
Breast Cancer Res Treat. 2018 Jan;167(1):39-47. doi: 10.1007/s10549-017-4502-3.
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Shien T, Iwata H
Significance of primary lesion resection in Stage IV breast cancer
Jpn J Clin Oncol. 2017 May 1;47(5):381-384. doi: 10.1093/jjco/hyx027.
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Shien T, Tanaka T, Tanabe M, et al.
Evaluation of ALDH1 expression in ipsilateral breast cancer recurrence
Oncol Lett. 2017 Mar;13(3):1071-1077. doi: 10.3892/ol.2016.5538.
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Saiga M, Taira N, Kimata Y, et al.
Development of a Japanese version of the BREAST-Q and the traditional psychometric test of the mastectomy module for the assessment of HRQOL and patient satisfaction following breast surgery
Breast Cancer. 2017 Mar;24(2):288-298. doi: 10.1007/s12282-016-0703-6.
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Hara A, Taira N, Mizoo T, et al.
N-acetyltransferase 2 polymorphism and breast cancer risk with smoking: a case control study in Japanese women
Breast Cancer. 2017 Mar;24(2):254-262. doi: 10.1007/s12282-016-0696-1.
2016
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Soh J, Toyooka S, Matsuo K, et al.
Ethnicity affects EGFR and KRAS gene alterations of lung adenocarcinoma
Oncol Lett. 2015 Sep;10(3):1775-1782. doi: 10.3892/ol.2015.3414.
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Soh J, Okumura N, Nakata M, et al.
Randomized feasibility study of S-1 for adjuvant chemotherapy in completely resected Stage IA non-small-cell lung cancer: results of the Setouchi Lung Cancer Group Study 0701
Jpn J Clin Oncol. 2016 Aug;46(8):741-7. doi: 10.1093/jjco/hyw062.
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Sugimoto S, Miyoshi K, Yamane M, et al.
Lung transplantation for diffuse panbronchiolitis: 5 cases from a single centre
Interact Cardiovasc Thorac Surg. 2016 May;22(5):679-81. doi: 10.1093/icvts/ivw008.
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Suzawa K, Toyooka S, Sakaguchi M, et al.
Antitumor effect of afatinib, as a human epidermal growth factor receptor 2-targeted therapy, in lung cancers harboring HER2 oncogene alterations
Cancer Sci. 2016 Jan;107(1):45-52. doi: 10.1111/cas.12845.
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Suzawa K, Yamamoto H, Murakami T, et al.
Establishment and molecular characterization of cell lines from Japanese patients with malignant pleural mesothelioma
Oncol Lett. 2016 Jan;11(1):705-712. doi: 10.3892/ol.2015.3955.
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Shien K, Toyooka S, Soh J, et al.
Clinicopathological characteristics and lymph node metastasis pathway of non-small-cell lung cancer located in the left lingular division
Interact Cardiovasc Thorac Surg. 2015 Jun;20(6):791-6. doi: 10.1093/icvts/ivv062.
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Watanabe M, Yamamoto H, Hashida S, et al.
Primary pulmonary melanoma: a report of two cases
World J Surg Oncol. 2015 Sep 17;13:274. doi: 10.1186/s12957-015-0695-2.
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Watanabe M, Yamamoto H, Eikawa S, et al.
Study about the Efficacy of Metformin to Immune Function in Cancer Patients
Acta Med Okayama. 2016 Aug;70(4):327-30. doi: 10.18926/AMO/54514.
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Taira N, Arai M, Ito Y, et al.
The Japanese Breast Cancer Society clinical practice guidelines for epidemiology and prevention of breast cancer, 2015 edition
Breast Cancer. 2016 May;23(3):343-56. doi: 10.1007/s12282-016-0673-8.
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Taira N, Fujisawa T, Araki K, et al.
Cohort Study of Secondary Endocrine Therapy in Metastatic Breast Cancer with a Poor Response to Initial Endocrine Therapy
J Clin Trials 6,2016
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Ito M, Shien T, Kaji M, et al.
Correlation between 18F-fluorodeoxyglucose Positron Emission Tomography/computed Tomography and Clinicopathological Features in Invasive Ductal Carcinoma of the Breast
Acta Med Okayama. 2015;69(6):333-8. doi: 10.18926/AMO/53907.
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Ito M, Shien T, Omori M, et al.
Evaluation of aldehyde dehydrogenase 1 and transcription factors in both primary breast cancer and axillary lymph node metastases as a prognostic factor
Breast Cancer. 2016 May;23(3):437-44. doi: 10.1007/s12282-015-0583-1.
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Iwamoto T, Kumamaru H, Miyata H, et al.
Distinct breast cancer characteristics between screen- and self-detected breast cancers recorded in the Japanese Breast Cancer Registry
Breast Cancer Res Treat. 2016 Apr;156(3):485-494. doi: 10.1007/s10549-016-3770-7.
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Iwamoto T, Kelly C, Mizoo T, et al.
Relative Prognostic and Predictive Value of Gene Signature and Histologic Grade in Estrogen Receptor-Positive, HER2-Negative Breast Cancer
Clin Breast Cancer. 2016 Apr;16(2):95-100.e1. doi: 10.1016/j.clbc.2015.10.004.
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Miyoshi Y, Shien T, Ogiya A, et al.
Differences in expression of the cancer stem cell marker aldehyde dehydrogenase 1 among estrogen receptor-positive/human epidermal growth factor receptor type 2-negative breast cancer cases with early, late, and no recurrence
Breast Cancer Res. 2016 Jul 2;18(1):73. doi: 10.1186/s13058-016-0731-3.
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Kimura K, Nakayama M, Naito I, et al.
Human collagen XV is a prominent histopathological component of sinusoidal capillarization in hepatocellular carcinogenesis
Int J Clin Oncol. 2016 Apr;21(2):302-309. doi: 10.1007/s10147-015-0888-2
2015
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Miyoshi S, Shien K, Toyooka S, et al.
Validity of using lobe-specific regional lymph node stations to assist navigation during lymph node dissection in early stage non-small cell lung cancer patients
Surg Today. 2014 Nov;44(11):2028-36. doi: 10.1007/s00595-013-0772-5.
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Tao H, Shien K, Soh J, et al.
Density of tumor-infiltrating FOXP3+ T cells as a response marker for induction chemoradiotherapy and a potential prognostic factor in patients treated with trimodality therapy for locally advanced non-small cell lung cancer
Ann Thorac Cardiovasc Surg. 2014;20(6):980-6. doi: 10.5761/atcs.oa.13-00237.
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Oto T, Miyoshi K, Sugimoto S, et al.
Living related donor middle lobe lung transplant in a pediatric patient
J Thorac Cardiovasc Surg. 2015 Mar;149(3):e42-4. doi: 10.1016/j.jtcvs.2014.10.102.
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Toyooka S, Soh J, Yamamoto H, et al.
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